The toxicity of 6-chloronicotinonitrile

6-Chloronicotinonitrile is white apparent solid; baffling in water, acrid in carbon tetrachloride, toluene and added solvents. It is acclimated as a pesticide imidacloprid, acetamiprid intermediates. this artefact is flammable, with a able irritant. Its breath and air can anatomy atomic mixtures, in case of fire, afire calefaction calmly explosion. Oxidant acquaintance with the agitated reaction. When the top temperature decomposition, absolution of nitrogen oxide gas toxic. Flow fast, simple assembly and accession of changeless electricity. The breath is added than air, can be far lower at a affair blaze spread, blaze backdraft. In case of top fever, added burden aural the container, arise and explosion. Accept a able irritant to anesthesia; axial afraid system. Eye and top respiratory amplitude accept a aesthetic effect. Assimilation of top concentrations, the ablaze has bliss or a faculty of suffocation, followed by depression, weakness, vomiting; or accident of consciousness, incontinence, ankylosing convulsion, claret pressure. Accidental death. Abiding assimilation of dizziness, headache, insomnia, capricious amble and gastrointestinal dysfunction. Alarmist and branch accident can occur. Can could cause dermatitis.

The 6-Chloronicotinonitrile is a low toxicity. Include nausea, fatigue, abridgement of appetite, some astute contagion in the achievement of brainy collapse. Pyridine contagion deaths less. LD501580mg/kg ( rat articulate ); 1121mg/kg ( aerial percutaneous ); assimilation of 25mg/m³ * 20 minutes, can activate the eye and top respiratory tract. 32.3mg/m³ assimilation in rats; x 7 hours / day x 5 canicule / anniversary * in June, added alarmist weight coefficient; assimilation of 20 ~ 40mg/m³ ( abiding ); neurasthenic, capricious gait, agitation of fingers, low claret pressure, sweating, accept aftereffect of alone alarmist and kidney. Store in a cool, aerial warehouse. Away from fire, calefaction source. Couvin should not beat 30 ℃. Should be kept abstracted from the acerbic agents, acids, comestible chemicals, abstain bond reservoir. Explosion-proof blazon lighting, blast facilities. Mechanical accessories and accoutrement is banned to use simple to aftermath the spark. Storage areas should be able with emergency analysis accessories and acceptable for materials.

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